Risk assessment of N-nitrosamines in balloons - Expert Opinion, 11 April 2002
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چکیده
1. Problem Various starting substances and additives are needed to produce consumer products based on natural and synthetic rubber. They include vulcanisation accelerators from the group of dithiocarbamates and thiurames which are converted during the vulcanisation process into N-nitrosamines and nitrosatable amines. Migratable levels of N-nitrosamines and nitrosatable amines have been repeatedly detected in official examinations of balloons in recent years. The following compounds were found: dimethylnitrosamine, diethylnitrosamine, dibutylnitrosamine and the amines which can form these nitrosamines. A health assessment is undertaken here of these levels and measures are proposed for precautionary consumer health protection. The basis for health assessment is firstly the toxic potency which can be established in animal experiments and secondly the estimation of exposure. Furthermore, other aspects like species differences and the special sensitivity of children to some specific noxae must be taken into account.
منابع مشابه
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تاریخ انتشار 2006